E88.3
Billable codeTumor lysis syndrome
The ICD-10 code for tumor lysis syndrome is E88.3.
Clinical notes
Also known as
Alternate wording, synonyms, or specific conditions that fall under this code, listed to help confirm you've picked the right one.
- Tumor lysis syndrome (spontaneous)
- Tumor lysis syndrome following antineoplastic drug chemotherapy
Use additional code
This code represents an underlying condition. When a related manifestation is also present, coding convention calls for an additional code to be listed after this one.
- code for adverse effect, if applicable, to identify drug (T45.1X5)
Documentation support
General coding-documentation guidance — not a substitute for payer-specific requirements or professional coding judgment.
- •If the associated manifestation or related condition noted above is also documented, an additional code should be reported alongside this one.
- •As a general rule, code to the highest level of specificity supported by the documentation in the medical record.
Related codes in this category
- E88.0Disorders of plasma-protein metabolism, not elsewhere classifiednon-billable header
- E88.1Lipodystrophy, not elsewhere classifiednon-billable header
- E88.2Lipomatosis, not elsewhere classified
- E88.4Mitochondrial metabolism disordersnon-billable header
- E88.8Other specified metabolic disordersnon-billable header
- E88.9Metabolic disorder, unspecified
- E88.AWasting disease (syndrome) due to underlying condition
- E88.3Tumor lysis syndrome
ICD-9-CM equivalent
Informational only — GEM mappings are approximate, not guaranteed one-to-one equivalents. Verify before use in billing.
- 27788
Associated MS-DRGs
E88.3 can serve as the principal diagnosis for these Medicare Severity Diagnosis-Related Groups.
Informational only — actual DRG assignment also depends on procedures, complications/comorbidities (CC/MCC), discharge status, and payer-specific rules not reflected here.