E88
Header — not billableOther and unspecified metabolic disorders
The ICD-10 code for other and unspecified metabolic disorders is E88.
E88 is a non-billable header code. It groups related conditions but cannot be used on its own for reimbursement — select one of the 8 more specific codes below.
Clinical notes
Excludes1 (not coded here)
An Excludes1 note is a pure exclusion: the excluded condition and this code should never be reported together, because the two conditions cannot occur at the same time (e.g. a congenital form vs. an acquired form of the same disease).
- histiocytosis X (chronic) (C96.6)
Use additional code
This code represents an underlying condition. When a related manifestation is also present, coding convention calls for an additional code to be listed after this one.
- codes for associated conditions
Documentation support
General coding-documentation guidance — not a substitute for payer-specific requirements or professional coding judgment.
- •This is a non-billable header code. Documentation must support a more specific child code before this diagnosis can be reported on a claim.
- •This code describes an unspecified presentation. If the medical record documents a more specific detail (e.g. laterality, type, or affected site), a more specific sibling code should be used instead — see Related codes below.
- •Confirm the excluded condition(s) listed above are not also present — Excludes1 conditions cannot be coded together with this one.
- •If the associated manifestation or related condition noted above is also documented, an additional code should be reported alongside this one.
- •As a general rule, code to the highest level of specificity supported by the documentation in the medical record.
Child codes under E88
- E88.0Disorders of plasma-protein metabolism, not elsewhere classifiednon-billable header
- E88.1Lipodystrophy, not elsewhere classifiednon-billable header
- E88.2Lipomatosis, not elsewhere classified
- E88.3Tumor lysis syndrome
- E88.4Mitochondrial metabolism disordersnon-billable header
- E88.8Other specified metabolic disordersnon-billable header
- E88.9Metabolic disorder, unspecified
- E88.AWasting disease (syndrome) due to underlying condition
Related codes in this category
- E70Disorders of aromatic amino-acid metabolismnon-billable header
- E71Disorders of branched-chain amino-acid metabolism and fatty-acid metabolismnon-billable header
- E72Other disorders of amino-acid metabolismnon-billable header
- E73Lactose intolerancenon-billable header
- E74Other disorders of carbohydrate metabolismnon-billable header
- E75Disorders of sphingolipid metabolism and other lipid storage disordersnon-billable header
- E76Disorders of glycosaminoglycan metabolismnon-billable header
- E77Disorders of glycoprotein metabolismnon-billable header
- E78Disorders of lipoprotein metabolism and other lipidemiasnon-billable header
- E79Disorders of purine and pyrimidine metabolismnon-billable header
- E80Disorders of porphyrin and bilirubin metabolismnon-billable header
- E83Disorders of mineral metabolismnon-billable header
- E84Cystic fibrosisnon-billable header
- E85Amyloidosisnon-billable header
- E86Volume depletionnon-billable header
- E87Other disorders of fluid, electrolyte and acid-base balancenon-billable header
- E88Other and unspecified metabolic disordersnon-billable header