Z16.12
Billable codeExtended spectrum beta lactamase (ESBL) resistance
The ICD-10 code for extended spectrum beta lactamase (esbl) resistance is Z16.12.
Clinical notes
Excludes2 (not included here)
An Excludes2 note means the excluded condition is not part of this one, but a patient can have both at the same time — in that case both codes may be reported together.
- Methicillin resistant Staphylococcus aureus infection in diseases classified elsewhere (B95.62)
Documentation support
General coding-documentation guidance — not a substitute for payer-specific requirements or professional coding judgment.
- •As a general rule, code to the highest level of specificity supported by the documentation in the medical record.
Related codes in this category
- Z16.10Resistance to unspecified beta lactam antibiotics
- Z16.11Resistance to penicillins
- Z16.13Resistance to carbapenem
- Z16.19Resistance to other specified beta lactam antibiotics
- Z16.12Extended spectrum beta lactamase (ESBL) resistance
ICD-9-CM equivalent
Informational only — GEM mappings are approximate, not guaranteed one-to-one equivalents. Verify before use in billing.
- V091Approximate match
Associated MS-DRGs
Z16.12 can serve as the principal diagnosis for these Medicare Severity Diagnosis-Related Groups.
Informational only — actual DRG assignment also depends on procedures, complications/comorbidities (CC/MCC), discharge status, and payer-specific rules not reflected here.