R65.1
Header — not billableSystemic inflammatory response syndrome (SIRS) of non-infectious origin
The ICD-10 code for systemic inflammatory response syndrome (sirs) of non-infectious origin is R65.1.
R65.1 is a non-billable header code. It groups related conditions but cannot be used on its own for reimbursement — select one of the 2 more specific codes below.
Clinical notes
Code first
This code represents a manifestation of an underlying disease. Coding convention requires the underlying (etiology) code to be sequenced first, with this code listed second.
Excludes1 (not coded here)
An Excludes1 note is a pure exclusion: the excluded condition and this code should never be reported together, because the two conditions cannot occur at the same time (e.g. a congenital form vs. an acquired form of the same disease).
- sepsis- code to infection
- severe sepsis (R65.2)
Documentation support
General coding-documentation guidance — not a substitute for payer-specific requirements or professional coding judgment.
- •This is a non-billable header code. Documentation must support a more specific child code before this diagnosis can be reported on a claim.
- •Confirm the excluded condition(s) listed above are not also present — Excludes1 conditions cannot be coded together with this one.
- •This code represents a manifestation. Documentation should identify the underlying condition, which must be coded first.
- •As a general rule, code to the highest level of specificity supported by the documentation in the medical record.
Related codes in this category
- R65.2Severe sepsisnon-billable header
- R65.1Systemic inflammatory response syndrome (SIRS) of non-infectious originnon-billable header