10ICD Code Hub

D89.3

Billable code

Immune reconstitution syndrome

The ICD-10 code for immune reconstitution syndrome is D89.3.

Clinical notes

Also known as

Alternate wording, synonyms, or specific conditions that fall under this code, listed to help confirm you've picked the right one.

  • Immune reconstitution inflammatory syndrome [IRIS]

Use additional code

This code represents an underlying condition. When a related manifestation is also present, coding convention calls for an additional code to be listed after this one.

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Documentation support

General coding-documentation guidance — not a substitute for payer-specific requirements or professional coding judgment.

Related codes in this category

ICD-9-CM equivalent

Informational only — GEM mappings are approximate, not guaranteed one-to-one equivalents. Verify before use in billing.

View full ICD-10 → ICD-9 crosswalk →

Associated MS-DRGs

D89.3 can serve as the principal diagnosis for these Medicare Severity Diagnosis-Related Groups.

Informational only — actual DRG assignment also depends on procedures, complications/comorbidities (CC/MCC), discharge status, and payer-specific rules not reflected here.