D57.21
Header — not billableSickle-cell/Hb-C disease with crisis
The ICD-10 code for sickle-cell/hb-c disease with crisis is D57.21.
D57.21 is a non-billable header code. It groups related conditions but cannot be used on its own for reimbursement — select one of the 6 more specific codes below.
Documentation support
General coding-documentation guidance — not a substitute for payer-specific requirements or professional coding judgment.
- •This is a non-billable header code. Documentation must support a more specific child code before this diagnosis can be reported on a claim.
- •As a general rule, code to the highest level of specificity supported by the documentation in the medical record.
Child codes under D57.21
- D57.211Sickle-cell/Hb-C disease with acute chest syndrome
- D57.212Sickle-cell/Hb-C disease with splenic sequestration
- D57.213Sickle-cell/Hb-C disease with cerebral vascular involvement
- D57.214Sickle-cell/Hb-C disease with dactylitis
- D57.218Sickle-cell/Hb-C disease with crisis with other specified complication
- D57.219Sickle-cell/Hb-C disease with crisis, unspecified
Related codes in this category
- D57.20Sickle-cell/Hb-C disease without crisis
- D57.21Sickle-cell/Hb-C disease with crisisnon-billable header